vs Beta-Blockers
LUMIGAN proven to offer superior IOP-lowering efficacy to timolol
Replacing timolol with LUMIGAN in a real-world trial results in lower mean IOP
LUMIGAN efficacy maintained through 2 years
LUMIGAN achieves additional mean IOP reduction when replacing beta-blockers
LUMIGAN proven to offer superior IOP-lowering efficacy to timolol
Mean IOP reduction at 10 AM 7
Average of 2.6 mm Hg greater reduction
Data were pooled from two 12-month, pivotal, randomized, parallel-group, double-masked, active-controlled, comparison clinical trials of 715 patients with elevated IOP (mean baseline of 26 mm Hg) following a washout period of their previous medications. Scheduled visits were at prestudy, baseline (day 0), weeks 2 and 6, and months 3, 6, and 12.
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Replacing timolol with LUMIGAN in a real-world trial results in lower mean IOP
Effects of LUMIGAN replacement of beta-blocker therapy on mean IOP 8
Replacement yields 20% additional reduction
Study was an open-label, noncomparative, surveillance trial involving 6767 patients from over 1400 clinical sites with over 1400 physicians. Data presented represented a subgroup of 587 patients who were on beta-blocker monotherapy prior to use of LUMIGAN ophthalmic solution.
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LUMIGAN efficacy maintained through 2 years
Mean IOP through 2 years, 10 AM 3
Over 2.4 mm Hg greater reduction
Data were from a 12-month pivotal extension of a multicenter, randomized, double-masked, 1-year, clinical trial. Patients were treated with bimatoprost 0.03% QD, bimatoprost 0.03% BID, or timolol 0.5% BID. Study visits took place at months 15, 18, 21, and 24. IOP was measured at 8 AM and 10 AM.
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LUMIGAN achieves additional mean IOP reduction when replacing beta-blockers
Additional mean IOP reduction at week 12 after replacing timolol with LUMIGAN 13
4.2 mm Hg additional reduction†
Data were from an open-label, 12-week evaluation of LUMIGAN in 55 patients with glaucoma or ocular hypertension who were insufficiently responsive to topical beta-blockers. Treated baseline was 20.9 mm Hg prior to LUMIGAN replacement. IOP measurements were taken at weeks 6 through 12.† Results at week 12 based on 46 patients who completed the study.
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