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African American Populations

LUMIGAN achieves lower mean IOP than timolol in black and non-black patients
LUMIGAN offers greater IOP reduction than travopost, even in African Americans

LUMIGAN achieves lower mean IOP than timolol in black and non-black patients

Overall mean IOP (pooled follow-up visits) for each time of day in blacks and non-blacks 20

Significantly lower than timolol in blacks and non-blacks

Data were from a randomized, pivotal double-masked, multicenter, parallel-group, 12-month trial of 132 patients randomized to receive either timolol 0.5% BID or bimatoprost QD (vehicle given in morning). Scheduled visits were at prestudy, day 0 (baseline), weeks 2 and 6, and months 3, 6, 9, and 12.

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LUMIGAN offers greater IOP reduction than travopost, even in African Americans

Mean IOP at each study visit 19

LUMIGAN performance in black patients

Data were from a randomized, investigator-masked, multicenter, parallel-design trial comparing the IOP-lowering efficacy of bimatoprost 0.03% and travoprost 0.004% in African Americans with glaucoma or ocular hypertension. After a washout of all ocular hypotensive agents, patients were assigned to bimatoprost once daily (n = 16) or travoprost once daily (n = 15) for 3 months. Study visits were at baseline and months 1, 2, and 3. Differences were not statistically significant, probably due to a small sample size.

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LUMIGAN (bimatoprost ophthalmic solution) 0.03% is for the treatment of high eye pressure, also called intraocular pressure (IOP), in people with open-angle glaucoma or ocular hypertension.

Important Safety Information
LUMIGAN (bimatoprost ophthalmic solution) 0.03% has been reported to cause darkening (pigmentation) of eye color, eyelid skin and eyelashes, as well as increased growth of eyelashes. Pigmentation changes can increase as long as LUMIGAN is used. After stopping LUMIGAN, darkening of eye color is likely to be permanent while darkening of the eyelid skin and eyelash changes may be reversible. The effects of increased darkening beyond 5 years are not known.

The most common side effects are eye redness,  growth of eyelashes,  and itchy eyes.


 
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